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16S rRNA Gene Sequencing vs. Shotgun Metagenomic Sequencing

Are you a company, lab or researcher planning a new microbiome study? If so, you are probably considering whether to conduct 16S rRNA gene sequencing or shotgun metagenomic sequencing. Although 16S rRNA gene sequencing has been more commonly used for microbiome studies to date, shotgun...

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Our Team Perspectives on World Microbiome Day

Here at Microbiome Insights, we are excited to celebrate the 3rd annual World Microbiome Day. The theme for World Microbiome Day 2020 is diversity. With this in mind, our team shared insights on diversity, the microbiome, and their perspectives for future microbiome research. 

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Introducing the Microbiome Study Guide, a Guide to Microbiome Research

It's no secret that the microbiome is getting traction every day with new research and discoveries. Being part of the discussion and performing studies in this important area of science shouldn't be a challenge. That's why our team created our new comprehensive Microbiome Study Guide.

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Christine Pierce on the microbiome and cancer, part II: Optimizing treatment

This blog post is Part II in a series on the microbiome and cancer. See here for Part I.

Attempting to understand the microbiome’s role in cancer etiology for possible prevention and diagnosis of various cancers is certainly worthwhile. But since each type of cancer probably has a highly nuanced...

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Christine Pierce on the microbiome and cancer, part I: Cancer etiology

This blog post is Part I in a two-part series on the microbiome and cancer. See here for Part II.

Some of the earliest-observed links between the human microbiome and cancer were the distinct patterns found in the microbiomes of healthy individuals compared to those with various carcinomas....

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The science behind Bill Gates’ vision: Will next-generation sequencing realistically contribute to solving the problem of child undernutrition?

In a recent lecture at the University of Cambridge, Bill Gates argued that the key to solving child malnutrition, one of the biggest global contributors to inequity, lies in deeper understanding of the gut microbiome. Much microbiome research has focussed on the influence of the gut microbiome...

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Shallow Shotgun Sequencing: A Primer

It is common for microbiome researchers to struggle over the choice between 16S sequencing or shotgun metagenome sequencing (SMS) for their study. When deciding which sequencing technique to use, it is essential to consider a number of factors including the research question, study design and...

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Considerations when choosing a collection device for your fecal samples

With so many options of fecal collection devices available for gut microbiome studies, how do you choose the best one for your research?

The primary purpose of a sample collection device is to capture a representative in vivo microbial sample capable of generating high-quality and reproducible...

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Why study probiotics for inflammatory bowel diseases?

Inflammatory bowel disease (IBD) is a collective term for chronic inflammatory diseases of the gastrointestinal (GI) tract, which include Crohn’s disease (CD) and ulcerative colitis (UC). These conditions are characterized by alternating phases of inflammation and mucosal tissue damage (active...

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Interpreting your fecal short-chain fatty acid data

Humans are unable to digest the bulk of dietary fibres without the help of anaerobic bacterial populations that convert the indigestible compounds to a form we are readily able to use. Short-chain fatty acids (SCFAs) are bioactive molecules that are a metabolic by-product of bacterial ...

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