Bradley van Paridon

New study helps disentangle gut microbiome signature of obesity versus type 2 diabetes

Obesity and type 2 diabetes (T2D) often occur together, and metabolic disease is linked to alterations in the gut microbiome but the changes associated uniquely with obesity versus T2D have been unclear. However, data now show that obesity along...

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Experts publish summary on microbiome contributions to age-related diseases and possible interventions to support healthy aging

Rapidly aging populations and the increasing prevalence of age-related diseases are issues facing many societies. While aging is a complex and not fully understood process, the microbiome and diet are receiving attention as potential ways to support...

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Mohn Lab uncovers gut microbiome differences in 3-month-old infants who go on to develop allergic disease

The inability of some infant microbiomes to perform carbohydrate metabolism may be a factor in the development of allergies later in life. Metagenomic analysis of the microbiomes of human infants who went on to develop allergies revealed a lack of...

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Landmark study tracks how microorganisms and metabolites change over time in inflammatory bowel disease

An ambitious new study followed 132 patients suffering from inflammatory bowel disease (IBD) for one year, in order to generate longitudinal molecular profiles of host and microbial activity. In doing so it captured the most comprehensive...

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Microbiome experts describe how to uncover contributions of microbial communities to climate change and ecosystem stability

The roles of complex microbial communities in soil and ocean environments is a relatively new area of inquiry, spurred on by the same advances in sequencing technology that have revealed the importance of human microbiomes in health. With emerging...

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Mouse study highlights role of NOD2 gene in gut microbiota resilience following antibiotics

New investigations using a gene knockout mouse model showed that neonatal exposure to antibiotics had a long-lasting effect on both the microbial community and mucosal immunity in the gut. The data also shone light on how the Nod2 gene alters the...

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New work shows gut microbial taxa might vary, but function is stable in people with Crohn's disease in remission

The numbers, types, and functions of gut microbes and the molecules they produce vary greatly over time and between individuals; however, there is new evidence showing that the metabolic function these microbes perform is conserved in some cases....

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Microbiome Insights scientific advisory board member Curtis Huttenhower contributes to research identifying thousands of new human microbiome species

Thousands of new microbial species making up the human microbiome have been identified from metagenome samples collected around the world. By reconstructing the microbial genomes found in over 9000 metagenome datasets, the microbial genomes of the...

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Novel combination of techniques improves identification of soil bacteria involved in wood decomposition: The latest from Mohn lab

In a bid to overcome the limitations of what scientists found previously from culture-dependent studies, new research shows stable isotope probing, coupled with next-generation sequencing techniques, can be used to identify which organisms living in...

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Stanford group draws wide expertise from Microbiome Insights & others to complete Chan Zuckerberg Biohub's Tabula Muris project

A detailed database of transcriptomic data from over 100,000 individual cells taken from the mouse model organism Mus musculus, titled Tabula Muris, is now available for use by biomedical researchers around the world. This work, completed by the The...

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